| 摘要 |
A microfluidics device and method for sample loading, concentrating, mixing, and/or reacting is disclosed. The device has a microchannel network that includes a channel segment communicating with first and second reservoirs. A projection formed on a wall portion of the channel segment terminates therein at a point or edge. When a voltage potential is applied across the two reservoirs, the projection functions to create an electric field gradient within the channel segment that causes charged components in the channel segment to concentrate in the region of the projection. The device is useful, for example, in loading a sample of dilute charged components for electrophoretic separation in the device.
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