发明名称 |
Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien |
摘要 |
The invention relates to a process for the preparation of L-amino acids, in which the following steps are carried out: a) fermentation of the coryneform bacteria which produce the desired L-amino acid and in which at least the gene which codes for the C4-dicarboxylate transport protein is attenuated, b) concentration of the desired L-amino acid in the medium or in the cells of the bacteria, and c) isolation of the L-amino acid, and optionally bacteria in which further genes of the biosynthesis pathway of the desired L-amino acid are additionally enhanced are employed, or bacteria in which the metabolic pathways which reduce the formation of the desired L-amino acid are at least partly eliminated are employed.
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申请公布号 |
DE10162650(A1) |
申请公布日期 |
2003.07.03 |
申请号 |
DE20011062650 |
申请日期 |
2001.12.20 |
申请人 |
DEGUSSA AG |
发明人 |
BREHME, JENNIFER;SCHISCHKA, NATALIE;MARX, ACHIM |
分类号 |
C12N1/21;C12N15/31;C12P13/08;(IPC1-7):C12N1/21;C12P13/04 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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