NUCLEOTIDE POLYMORPHISMS ASSOCIATED WITH OSTEOPOROSIS

摘要

The invention relates to polynucleotides associated with susceptibility to low bone mineral density and/or bone damage generally associated with human diseases, and in particular to osteoporosis. The invention further relates to polymorphic polynucleotides associated with osteoporosis. The invention provides methods of determining if a particular polymorphism predisposes an individual to or is associated with the development of osteoporosis. The invention also provides methods of detecting the presence of one or more polymorphism as an indicator of osteoporosis, and provides for use of novel polynucleotides of the invention in the development of drugs and in disease treatment.