发明名称 |
Quinolinecarboxylic acid derivative or salts thereof that have antimicrobial effect |
摘要 |
1-(6-amino-3,5-difluoropyridin-2-yl)-8-bromo-7-(3-ethylaminoazetidin-1 -yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is a quinolinecarboxylic acid derivative of formula (I) and salts thereof, which has excellent antimicrobial effects and oral absorption, and antimicrobial agents comprising the same is disclosed. This compound of formula (I) has characteristic features that, when administered orally, it has extremely high blood half-life and bioavailability while retaining properties that it has extremely high antimicrobial effects and has low toxicity. It can be used widely as preventives, therapeutics and the like for various infectious diseases.
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申请公布号 |
NZ516201(A) |
申请公布日期 |
2003.06.30 |
申请号 |
NZ20000516201 |
申请日期 |
2000.06.22 |
申请人 |
WAKUNAGA PHARAMACEUTICAL CO |
发明人 |
YAZAKI, AKIRA;NIINO, YOSHIKO;KURAMOTO, YASUHIRO;HIRAO, YUZO;OHSHITA, YOSHIHIRO;HAYASHI, NORIHIRO;AMANO, HIROTAKA |
分类号 |
A61K31/4709;A61P31/04;C07D401/14;(IPC1-7):C07D401/14;A61K31/470 |
主分类号 |
A61K31/4709 |
代理机构 |
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主权项 |
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地址 |
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