Promoting cell survival by inhibiting BARD1 apoptotic activity

摘要

The present invention provides a method for promoting cell survival, which method comprises inhibiting BARD1 activity. This method may be performed by contacting a cell with an agent that inhibits BARD1 activity. Such agent may be an agent that inhibits BARD 1 expression, such as a BARD1 antisense nucleic acid. The method of the invention is especially useful for alleviating damage in cells subjected to ischemia.