发明名称 |
TETRAHYDRO-HETEROCYCLOAZEPINYL PYRIMIDINE DERIVATIVES. |
摘要 |
<p>The invention relates to compounds of the general formula (I) wherein HET and R1 to R12 have the significances as defined in the specification, as well as their phamaceutically acceptable salts. The invention further relates to medicaments containing such compounds and a process for the preparation of such compounds. The compounds of formula (I) are group (I) mGluR antagonists and are therefore useful for the control or prevention of acute and/or chronic neurological disorders.</p> |
申请公布号 |
MXPA03000428(A) |
申请公布日期 |
2003.06.24 |
申请号 |
MX2003PA00428 |
申请日期 |
2001.07.16 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
MUTEL, VINCENT |
分类号 |
A61K31/55;A61P1/08;A61P3/08;A61P9/02;A61P9/04;A61P9/10;A61P13/02;A61P15/00;A61P21/02;A61P25/00;A61P25/02;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/34;A61P25/36;A61P27/02;A61P31/18;C07D487/04;C07D495/04;C07D513/04 |
主分类号 |
A61K31/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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