| 摘要 |
FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to method for preparing alpha-acetylene gamma-diols used as an intermediate product in synthesis lacquer, glues, flotating reagents, corrosion inhibitors, fragrant and medicinal substances. Method involves interaction of acetylene compound with ketones of the general formula R-CO-R' where R, R' mean alkyl, aryl, alkoxyl, hydroxyalkyl, cycloalkyl, heterocycle in the presence of alkaline metal hydroxides, at stirring in solvent followed by removal of solvent, hydrolysis of prepared diol-alkaline complex and isolation of the end product. As acetylene compound acetylene or acetylene alcohol of the general formula alpha is used where R'', R''' mean hydrogen atom, alkyl, aryl, alkoxyl, cycloalkyl, heterocycle and liquid ammonia is used as solvent. Interaction is carried out in the molar ratio ammonia : acetylene compound = (6-50) : : 1, molar ratio alkaline metal hydroxide : acetylene compound gamma 1, at temperature (-15)-(+45) C and in the presence of aliphatic alcohols taken in the amount no exceeding 300 molar % with respect to alkaline metal hydroxide. Isolation of the end product is carried out by extraction and distillation of extractant and low-boiling impurities. As a rule, molar ratio ketone : acetylene = 2:1 and molar ratio ketone : acetylene alcohol = 1:1. Method ensures to improve indices of intensity and selectivity of process. EFFECT: improved preparing method. 4 cl, 4 tbl
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