| 摘要 |
<p>The invention provides a method for detecting apoptosis in a cell comprising detecting an alteration in any one of - i) a TGNP polypeptide having an amino acid sequence as set out in SEQ ID NO: 1; ii) a polypeptide having at least 80 % homology with i); iii) a nucleic acid encoding a polypeptide having the sequence set out in i) or ii); iv) a nucleic acid which hybridises under stringent conditions to the sequence set out in iii); or v) the complement of iii) or iv). The invention accordingly provides a method of modulating apoptosis by modulating TGNP gene expression and a method for identifying genes associated with TGNP gene expression and thus identifying other genes associated with apoptosis. The invention also provides a novel nucleic acid sequence encoding the promoter region for TGNP.</p> |
