发明名称 Cardioprotective phosphonates and malonates
摘要 The present invention provides for pyridoxine phosphonate analogues such as, for example, ((2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridyl)alkylphosphonates, and (2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridyl)azaalkylphosphonates) and to pyridoxine malonate analogues, such as, for example, ((2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridylmethyl)malonates), pharmaceutical compositions, and methods for treatment of cardiovascular and related diseases, and diabetes mellitus and related diseases.
申请公布号 US2003114677(A1) 申请公布日期 2003.06.19
申请号 US20020282325 申请日期 2002.10.28
申请人 MEDICURE INTERNATIONAL INC. 发明人 HAQUE WASIMUL
分类号 C07D491/056;A61K31/436;A61K31/44;A61K31/662;A61K31/683;A61K38/28;A61K45/00;A61P3/00;A61P3/04;A61P3/10;A61P7/02;A61P9/00;A61P9/04;A61P9/06;A61P9/08;A61P9/10;A61P9/12;A61P13/02;A61P43/00;C07D213/65;C07D213/66;C07F9/58;C07F9/6561;(IPC1-7):A61K31/675 主分类号 C07D491/056
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