PURPOSE: Provided is a transformed mouse expressing the HPV E6 gene which is usefully used in screening tumor gene and tumor treating agent since tumor development occurs at the late stage. CONSTITUTION: An animal excluding human beings is transformed to express HPV(human papilloma virus) E6 gene inducing the mammary gland tumor. In the transformed animal, the HPV E6 gene is inserted into the chromosome of the animal and is operably linked to a beta-casein promotor. The chromosome is able to be body cells or sexual cells. The animal is mainly a mouse.
申请公布号
KR20030048253(A)
申请公布日期
2003.06.19
申请号
KR20010078140
申请日期
2001.12.11
申请人
KOREA FOOD & DRUG ADMINISTRATION
发明人
BAEK, SANG GI;CHAE, GAP YONG;CHO, JEONG SIK;CHO, YONG YEON;HWANG, DAE YEON;HWANG, JIN HUI;JANG, IN SEOK;KIM, YEON JU;KIM, YONG GYU;LIM, CHEOL JU;SHIN, DONG HWAN