METERING VALVE AND PHARMACEUTICAL METERED DOSE INHALER AND METHODS THEREOF

摘要

The invention is directed to a method of treating an elastomeric substrate comprising, in any suitable order, the acts of providing an elastomeric substrate in a bath comprising an alchohol and an alkaline material at a bath temerature effective for treatment. Other acts include providing ultrasonic energy at a treatment-effective frequency and power level to the bath for a time period sufficient to treat the elastomeric substrate; rinsing the treated elastomeric substrate with de-ionized water; and, drying the rinsed and treated elastomeric substrate.