发明名称 USE OF PRAMIPEXOLE TO TREAT AMYOTROPHIC LATERAL SCLEROSIS
摘要 The present invention is directed to compositions comprising pramipexole and the use of such compositions to treat neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS). As shown in Fig. 6B the mean +1- SEM serum 2,3-DHBA levels for the 12 ALS participants decreased signifacantly after pramipexole treatment.
申请公布号 CA2468747(A1) 申请公布日期 2003.06.19
申请号 CA20022468747 申请日期 2002.12.02
申请人 UNIVERSITY OF VIRGINIA PATENT FOUNDATION 发明人 BENNETT, JAMES P., JR.
分类号 C07D277/82;A61K;A61K31/425;A61K31/428;A61P21/00;(IPC1-7):A61K31/425 主分类号 C07D277/82
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