发明名称 |
N-BENZYLDIOXOTHIAZOLIDYLBENZAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME |
摘要 |
The present invention provides novel N- benzyldioxothiazolidylbenzamide derivatives that improve the insulin resistance and have potent hypoglycemic and lipid- lowering effects and processes for preparing the same, and relates to N-benzyldioxothiazolidylbenzamide derivatives characterized by being represented by a general formula (1) <See Formula I> [wherein R1 and R2 denote identically or differently hydrogen atoms, lower alkyl groups with carbon atoms of 1 to 4, lower alkoxy groups with carbon atoms of 1 to 3, lower haloalkyl groups with carbon atoms of 1 to 3, lower haloalkoxy groups with carbon atoms of 1 to 3, halogen atoms, hydroxyl groups, nitro groups, amino groups which may be substituted with lower alkyl group(s) with carbon atoms of 1 to 3 or hetero rings, or R1 and R2 link to form a methylenedioxy group, R3 denotes a lower alkoxy group with carbon atoms of 1 to 3, hydroxyl group or halogen atom, and dotted line indicates double bond or single bond in combination with solid line], and processes for preparing the same.
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申请公布号 |
CA2220698(C) |
申请公布日期 |
2003.06.17 |
申请号 |
CA19962220698 |
申请日期 |
1996.05.30 |
申请人 |
KYORIN PHARMACEUTICAL CO., LTD. |
发明人 |
TSUNODA, MASAKI;NOMURA, MASAHIRO;KINOSHITA, SUSUMU;MURAKAMI, KOJI;MAEDA, TOSHIO;SATOH, HIROYA;AWANO, KATSUYA |
分类号 |
C07D277/20;A61K31/425;A61K31/426;A61P3/06;A61P3/08;A61P3/10;C07C67/347;C07C69/76;C07C69/84;C07C69/92;C07D277/34;C07D417/12;(IPC1-7):C07D277/34 |
主分类号 |
C07D277/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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