| 发明名称 |
N-ARYL-N'-ARYLCYCLOALKYL-UREA DERIVATIVES AS MCH ANTAGONISTSFOR THE TREATMENT OF OBESITY |
| 摘要 |
The present invention discloses compounds of the formula I which, are novel antagonists for melanin-concentrating hormone (MCH), as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such MCH antagonists as well as metho ds of using them to treat obesity, metabolic disorders, eating disorders such a s hyperphagia, and diabetes.
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| 申请公布号 |
CA2468967(A1) |
申请公布日期 |
2003.06.12 |
| 申请号 |
CA20022468967 |
申请日期 |
2002.12.03 |
| 申请人 |
SCHERING CORPORATION |
发明人 |
CLADER, JOHN W.;PALANI, ANANDAN;XU, RUO;TANG, HAIQUN;SU, JING;MC BRIAR, MARK D. |
| 分类号 |
C07D295/12;A61K31/155;A61K31/17;A61K31/18;A61K31/277;A61K31/381;A61K31/40;A61K31/407;A61K31/4178;A61K31/427;A61K31/44;A61K31/4439;A61K31/444;A61K31/4453;A61K31/4465;A61K31/453;A61K31/4535;A61K31/454;A61K31/495;A61K31/496;A61K31/5375;A61K31/55;A61K31/64;A61K31/7034;A61K38/00;A61K38/28;A61K45/00;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P9/12;A61P25/18;A61P25/20;A61P25/22;A61P25/24;C07C275/30;C07D205/04;C07D207/06;C07D207/08;C07D207/10;C07D207/12;C07D207/14;C07D207/27;C07D209/52;C07D211/14;C07D211/22;C07D211/26;C07D211/34;C07D211/38;C07D211/44;C07D211/60;C07D211/70;C07D211/96;C07D213/75;C07D213/89;C07D233/24;C07D233/64;C07D241/04;C07D263/32;C07D295/13;C07D333/36;C07D401/06;C07D401/12;C07D405/04;C07D405/06;C07D409/04;C07D409/06;C07D413/06;C07D413/12;C07D491/048;(IPC1-7):C07D413/12;C07D403/12;A61K31/275;A61K31/397;C07C275/40;A61K31/445;A61K31/537 |
主分类号 |
C07D295/12 |
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