发明名称 |
NUCLEAR PROTEIN SHOCA - A COMPONENT OF THE WNT SIGNALLING PATHWAY |
摘要 |
An isolated Shoca polypeptide comprising: (i) the amino acid sequence of SEQ ID NO: 2 or SEQ ID NO: 4; or (ii) a variant thereof which is capable of interacting with a polypeptide of the wnt signalling pathway; or (iii) a fragment of (i) or (ii) which is capable of interacting with a polypeptide o f the wnt signalling pathway, a polypeptide encoding said polypeptide, a metho d for identifying a modulator of the wnt signalling pathway utilising said polypeptide or polynucleotide and methods of diagnosing and treating cancer.
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申请公布号 |
CA2469356(A1) |
申请公布日期 |
2003.06.12 |
申请号 |
CA20022469356 |
申请日期 |
2002.12.03 |
申请人 |
THE UNIVERSITY CHILDREN'S HOSPITAL OF BOTH CANTONS OF BASEL |
发明人 |
HOLLANDER, GEORG ANDREAS |
分类号 |
C12N15/09;A61K38/00;A61K38/16;A61K45/00;A61K47/48;A61K51/10;A61P35/00;C07K14/47;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12N15/63;C12Q1/02;C12Q1/68;G01N33/53;(IPC1-7):C12N15/12;A61K39/395 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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