CHIRAL LIGANDS FOR ASYMMETRIC CATALYSIS

摘要

The present invention is based around the discoveries that novel ligands of formula(4),and the opposite enantiomers thereof,(i)have utility as components of catalysts for asymmetric hydrogenation and(ii)are readily accessible by an efficient general synthetic route.In particular,ruthenium−diamine complexes of the ligands(4)are highly active and selective catalysts for the asymmetric hydrogenation of ketones.