| 摘要 |
New cosmetic or dermatological composition for local external use for the photoprotection of the skin and/or hair comprising (a) an organic insoluble filter compound and (b) a second filter comprising an amino-substituted derivative of 2-hydroxybenzophenone in a cosmetic base supporet. <??>The composition comprises :- a) An insoluble organic UV filter of particle size 10 nm - 5 mu ; and b) A derivative of an amino-substituted 2-hydroxybenzophenone of formula (I) :- - in which <??>R<1>, R<2>(identical or different) = H, 1 - 20C alkyl, 2 - 10C alkenyl, 3 - 10C cycloalkyl or 3 - 10C cycloalkenyl(R<1> and R<2> with N may form a 5 - 6 membered ring); <??>R<3>, R<4> (identical or different) = 1 - 20C alkyl, 2 - 10C alkenyl, 3 - 10C cycloalkyl or cycloalkenyl, 1 -12C alkoxy, 1 - 20C alkoxycarbonyl, 1 - 12C alkylamino or dialkylamino, aryl, or heteroaryl(optionally substituted) or a water soluble substituent from carboxylate, sulfonate or ammonium; <??>X = H, COOR<5> or CONR<6>R<7>(R<5>, R<6>, R<7> = H, 1 - 20C alkyl, 2 - 10C alkenyl, 3 - 10C cycloalkyl or cycloalkenyl, a group -(YO)o-Z or aryl); <??>Y = -(CH2)2-, -(CH2)3-, --(CH2)4-, or -CH-(CH3)-CH2-; <??>Z = -CH2CH3-, -CH2CH2CH3-, CH2CH2CH2CH3 or -CH(CH3)CH3; <??>m = 0 - 3; <??>n = 0 - 3; <??>0 = 1 - 2. <??>The primary and secondary filters are present in such proportions as to produce a synergistic activity to confer solar protection to factor UV-APPD. An Independent claim is also included for the use of the compositions.
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