| 摘要 |
<p>A process for synthesizing paclitaxel derivative compounds useful for the treatment of cancer, comprises protecting the hydroxyl group at C-2' position of a paclitaxel compound by reacting the same with a protecting group reagent to provide a protecting group (PG) at the C-2' position, converting the hydroxyl group at C-7 position of the paclitaxel compound to a methylthiomethyl ether, and deprotecting the C-2' position hydroxyl group through the removal of the protecting group reagent, thus yielding the final desired paclitaxel derivative product.</p> |
