| 发明名称 |
Linked peptide nucleic acids |
| 摘要 |
Novel peptide nucleic acids are disclosed which comprise nucleobases including C-pyrimidines and iso-pyrimidines. Suitable C-pyrimidines include pseudo-isocytosine and pseudo-uracil. Suitable iso-pyrimidine bases include iso-cytosine. Such compositions typically exhibit increased binding affinity.
|
| 申请公布号 |
US2003105286(A1) |
申请公布日期 |
2003.06.05 |
| 申请号 |
US20020188404 |
申请日期 |
2002.07.01 |
| 申请人 |
EGHOLM MICHAEL;NIELSEN PETER;BUCHARDT OLE;BUCHARDT D.;DUEHOLM KIM L.;CHRISTENSEN LEIF;COULL JAMES M.;KIELY JOHN;GRIFFITH MICHAEL |
发明人 |
EGHOLM MICHAEL;NIELSEN PETER;BUCHARDT OLE;BUCHARDT D.;DUEHOLM KIM L.;CHRISTENSEN LEIF;COULL JAMES M.;KIELY JOHN;GRIFFITH MICHAEL |
| 分类号 |
A61K38/00;C07H21/00;C07K5/06;C07K7/06;C07K7/08;C07K14/00;C12N15/10;C12N15/113;C12Q1/68;(IPC1-7):C07K14/00;C07K9/00 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
