摘要 |
The invention relates to the field of molecular recognition or detection of discontinuous or conformational binding sites of TNF alpha or epitopes corresponding to a binding molecule, in particular in relation to protein-protein protein-nucleic acid, nucleic acid-nucleic acid or biomolecule-ligand interactions. The invention provides a synthetic molecular library allowing testing for, identification, characterisation or detection of a discontinuous binding site of TNF alpha capable of interacting with a binding molecule, said library having been provided with a plurality of molecules, each molecule of said molecules comprising at least one first segment linked to a second segment, each segment having the capacity of being a potential single part of a discontinuous binding site. |
申请人 |
PEPSCAN SYSTEMS B.V.;SLOOTSTRA, JELLE, WOUTER;PUIJK, WOUTER, CORNELIS;VAN DIJK, EVERT |
发明人 |
SLOOTSTRA, JELLE, WOUTER;PUIJK, WOUTER, CORNELIS;VAN DIJK, EVERT |