发明名称 |
METHOD OF MONITORING THE EFFECT OF CATHEPSIN S INHIBITORS |
摘要 |
The present invention relates to a method for monitoring the effect of in vivo administration of Cathepsin S inhibitors by measuring accumulation of an intermediate degradation product of invariant chain (Ii), in particular the p10 Ii fragment, in blood of dosed subjects. |
申请公布号 |
EP1315966(A1) |
申请公布日期 |
2003.06.04 |
申请号 |
EP20010968093 |
申请日期 |
2001.08.24 |
申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
THURMOND, ROBIN;SUN, SIQUAN;KARLSSON, LARS |
分类号 |
G01N33/53;C12Q1/37;G01N33/573;(IPC1-7):G01N33/535;G01N33/545 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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