发明名称 |
GENE EXPRESSION, GENOME ALTERATION AND REPORTER EXPRESSION IN MYOFIBROBLASTS AND MYOFIBROBLAST-LIKE CELLS |
摘要 |
The invention relates to specific, regulatory sequence regions of the alpha smooth muscle actin gene (a-SMA gene), and fusion structures in which said regulatory sequence regions of the a-SMA gene are operationally linked to other functional nucleic acid sequences. The invention also relates to the use of said regulatory sequence regions for cell type specific and differentiation specific reporter expression, for cell type specific and differentiation specific gene changes (alteration, mutation) and for gene expression changes in cells and organisms. |
申请公布号 |
EP1315748(A2) |
申请公布日期 |
2003.06.04 |
申请号 |
EP20010962847 |
申请日期 |
2001.07.10 |
申请人 |
CELL CENTER COLOGNE GMBH |
发明人 |
ODENTHAL, MARGARETE;JUNG, DIANA |
分类号 |
A01K67/027;A61K38/00;A61K48/00;A61P1/16;A61P11/00;A61P13/12;A61P17/02;A61P19/08;A61P25/00;A61P35/00;C07K14/47;C12N1/15;C12N1/19;C12N5/10;C12N15/09;C12N15/85;C12Q1/02;G01N33/15;G01N33/50 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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