发明名称 |
INTEGRIN RECEPTOR INHIBITORS |
摘要 |
Provided are compounds of formula (I) wherein A, Q, W, X, Y, Z, R1 to R4, m and n are as defined herein. Compounds of the invention bind to alpha 4 integrin receptors and thereby inhibit binding of ligands for alpha 4 integrins which is useful for prophylactic and/or therapeutic treatment of diseases and conditions associated with alpha 4 integrins or their ligands. |
申请公布号 |
WO0216313(A3) |
申请公布日期 |
2003.05.30 |
申请号 |
WO2001US25865 |
申请日期 |
2001.08.16 |
申请人 |
GENENTECH, INC. |
发明人 |
ARTIS, DEAN, R.;JACKSON, DAVID, Y.;RAWSON, THOMAS, E.;REYNOLDS, MARK, E.;SUTHERLIN, DANIEL, P.;STANLEY, MARK, S. |
分类号 |
A61K31/195;A61K31/403;A61P1/04;A61P1/12;A61P1/16;A61P1/18;A61P3/10;A61P11/00;A61P11/02;A61P11/06;A61P15/14;A61P17/00;A61P17/06;A61P19/02;A61P25/28;A61P29/00;A61P37/00;A61P43/00;C07C233/25;C07C233/60;C07C233/81;C07C237/04;C07C237/20;C07C237/22;C07C237/42;C07D207/16;C07D207/48;C07D209/88;C07D403/12;C07D405/12 |
主分类号 |
A61K31/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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