发明名称 |
METHODS FOR IDENTIFYING AND VALIDATING POTENTIAL DRUG TARGETS |
摘要 |
This application provides methods for identifying and validating potential drug targets. In one aspect, the application provides a systematic method of creating a database of related protein or nucleic acid sequences with annotations of the potential disease associations of the sequences; and a method for testing the potential disease associations by means of a biological assay and validating the disease association by either decreasing expression of the sequence of interest or increasing expression of the sequence of interest.
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申请公布号 |
CA2468107(A1) |
申请公布日期 |
2003.05.30 |
申请号 |
CA20022468107 |
申请日期 |
2002.11.19 |
申请人 |
PROTEOLOGICS, INC. |
发明人 |
LEVY, AVISHAI;GREENER, TSVIKA;BEN-AVRAHAM, DANNY;ALROY, IRIS;REISS, YUVAL |
分类号 |
C12N15/09;A61K;A61K38/00;A61K48/00;A61P31/12;A61P35/00;C12Q;C12Q1/02;C12Q1/25;C12Q1/68;C12Q1/70;G01N33/48;G01N33/50;G01N33/53;G01N33/573;G06F17/30;G06F19/18;(IPC1-7):C12Q1/68;G06F19/00 |
主分类号 |
C12N15/09 |
代理机构 |
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地址 |
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