发明名称 |
Orally administered composition comprises antibiotic cefuroxime axetil in lipid coated particle form, sweetening system and texture modifier |
摘要 |
Composition (A) comprises cefuroxime axetil (I) in the form of particles, entirely enclosed in a coating of at least one lipid (insoluble in water but dispersing or decomposing in contact with gastrointestinal fluid), a bulk sweetener and a binder. (A) Also contains a sweetening system (II) and a texture modifier (III), in amounts so that the bitter taste of (I) is masked. An Independent claim is included for an orally administered medicament (preferably in aqueous suspension or granule form), comprising (A) together with carriers or excipients.
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申请公布号 |
FR2832635(A1) |
申请公布日期 |
2003.05.30 |
申请号 |
FR20020014587 |
申请日期 |
2002.11.21 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
FERNANDEZ MATILDE IBANEZ;GARRIZ EMILIO SANZ |
分类号 |
A61K9/10;A61K9/00;A61K9/14;A61K9/16;A61K9/30;A61K9/50;A61K31/545;A61K31/546;A61K47/20;A61K47/22;A61K47/26;A61K47/32;A61K47/36;A61K47/38;A61K47/42;A61P31/00;A61P31/04;(IPC1-7):A61K31/546 |
主分类号 |
A61K9/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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