Matrix assays in genomically indexed cells

摘要

A method for ascertaining the functional patterns of pharmacologically-important compounds by measuring the physiological effect of a plurality of compounds on a plurality of cells comprising the steps of: assaying the plurality of compounds to obtain a first set of data determining the physiological effect of each compound on each cell; assaying at least one known pharmaceutically-important compound to obtain a second set of data determining the physiological effect of the known pharmaceutically-important compound on each cell; and comparing the first and second sets of data to identify a compound having similar physiological effects as the known pharmaceutically-important compound thereby ascertaining its functional patterns.