DERIVATIVES OF K-252A

摘要

FIELD: organic chemistry, medicine. SUBSTANCE: invention relates to novel derivatives of K-252a (derivatives of indolocarbazole) represented by the general formula (I) and to method of enhancement of function and/or enhancement of survival of cholinoceptive neuron and method of enhancement of survival of cell in its death risk as far as compounds of the formula (I) inhibit production of interleukine-2 and exhibit immunosuppressive activity. Invention provides synthesis of new compounds that can be used in pharmacology. EFFECT: valuable medicinal and pharmacological properties of compounds. 14 cl, 4 tbl, 9 dwg