发明名称 DELIVERY OF DIAZEPAM THROUGH AN INHALATION ROUTE
摘要 The present invention relates to the delivery of diazepam through an inhalation route. Specifically, it relates to aerosols containing diazepam that are used in inhalation therapy. In a composition aspect of the present invention, the aerosol comprises particles comprising at least 5 percent by weight of diazepam. In a method aspect of the present invention, diazepam is delivered to a mammal through an inhalation route. The method comprises: a) heating a composition, wherein the composition comprises at least 5 percent by weight of diazepam, to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles, which is inhaled by the mammal. In a kit aspect of the present invention, a kit for delivering diazepam through an inhalation route to a mammal is provided which comprises: a) a composition comprising at least 5 percent by weight of diazepam; and, b) a device that forms a diazepam containing aerosol from the composition, for inhalation by the mammal.
申请公布号 WO03041693(A1) 申请公布日期 2003.05.22
申请号 WO2002US15820 申请日期 2002.05.15
申请人 ALEXZA MOLECULAR DELIVERY CORPORATION 发明人 RABINOWITZ, JOSHUA, D.;ZAFFARONI, ALEJANDRO, C.
分类号 A61K9/00;A61K9/72;A61K31/5513;(IPC1-7):A61K9/72;A61K31/551 主分类号 A61K9/00
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