发明名称 BIPHENYL-HYDROXAMAT MATRIX-METALLOPROTEINE INHIBITOR
摘要 Compounds of formula <IMAGE> or a pharmaceutically acceptable salt thereof inhibit matrix metalloproteinases and TNF alpha secretion and are useful in the treatment of inflammatory disease states. Also disclosed are matrix metalloproteinases and TNF alpha secretion inhibiting compositions and a method for inhibiting matrix metalloproteinases and TNF alpha secretion.
申请公布号 DE69627380(D1) 申请公布日期 2003.05.15
申请号 DE1996627380 申请日期 1996.11.13
申请人 ABBOTT LABORATORIES, ABBOTT PARK 发明人 FESIK, W.;SUMMERS, B.;DAVIDSEN, K.;SHEPPARD, S.;STEINMAN, H.;CARRERA, M.;FLORJANCIC, ALAN;HOLMS, H.
分类号 A61P19/02;A61K31/185;A61K31/275;A61P29/00;A61P35/04;A61P43/00;C07C259/06;C07C323/60;(IPC1-7):C07C259/06;A61K31/16 主分类号 A61P19/02
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