发明名称 |
BACTERIAL ION CHANNEL AND A METHOD FOR SCREENING ION CHANNEL MODULATORS |
摘要 |
The present invention relates to a functionally expressed bacterial voltage-sensitive ion-selective channel. The novel channel can be used in conjunction with mammalian ion channel pore-containing regions in assays for screening for compounds that modulate activity of the channel. One bacterial ion channel of the present invention, called NaChBac, is derived from Bacillus halodurans (GenBank#BAB05220 (8)). |
申请公布号 |
WO03040323(A2) |
申请公布日期 |
2003.05.15 |
申请号 |
WO2002US35395 |
申请日期 |
2002.11.05 |
申请人 |
CHILDREN'S MEDICAL CENTER CORPORATION;CLAPHAM, DAVID;REN, DEJIAN |
发明人 |
CLAPHAM, DAVID;REN, DEJIAN |
分类号 |
C07K14/32;C12N15/24 |
主分类号 |
C07K14/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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