| 发明名称 |
NOVEL 1,2,4-THIADIAZOLIUM DERIVATIVES AS MELANOCORTIN RECEPTOR MODULATORS |
| 摘要 |
The present invention is directed to novel 1,2,4-thiadiazol-2-ium derivatives of the formula (I); wherein R<1¿, R?2¿ and R?4¿ are ring containing radicals, R?3¿ is H, alkyl, alkenyl or alkynyl, useful as agonists or antagonists of the melanocortin receptor. More particularly, the compounds of the present invention are useful for the treatement of metabolic, CNS and dermatological disorders.
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| 申请公布号 |
WO03040118(A1) |
申请公布日期 |
2003.05.15 |
| 申请号 |
WO2002US35365 |
申请日期 |
2002.11.05 |
| 申请人 |
ORTHO-MCNEIL PHARMACEUTICAL CORPORATION |
发明人 |
EISINGER, MAGDALENA;FITZPATRICK, LOUIS, J.;LEE, DANIEL, H.;PAN, KEVIN;PLATA-SALAMAN, CARLOS;REITZ, ALLEN, B.;SMITH-SWINTOSKY, VIRGINIA, L.;ZHAO, BOYU |
| 分类号 |
A61K31/433;A61K31/4439;A61K31/5575;A61P3/00;A61P3/04;A61P3/08;A61P3/10;A61P15/10;A61P17/00;A61P17/10;A61P25/00;A61P25/28;A61P27/02;A61P27/06;A61P27/16;A61P31/04;A61P43/00;C07D285/08;C07D333/16;C07D333/28;C07D417/12;C07F9/40;H04R27/00;H04R29/00;(IPC1-7):C07D285/08 |
主分类号 |
A61K31/433 |
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