| 摘要 |
The invention concerns the use of 2-amino-thiazoline derivatives of formula (I), wherein: Y is a (CH2) methylene and X is selected among the following groups: O, NH, C1-C4 N-alkyl, N-Bn, N-Ph, N-(2-Py), N-(3-Py), N(4-Py), N-2-pyrimidyl, N-5-pyrimidyl, S, SO, SO2, CH2 or CHPh; or Y is a (C=O) carboxy and X is selected among the following groups: NH, N-Ph, N-(2-Py), N-(3-Py), N(4-Py), N-2-pyrimidyl, N-5-pyrimidyl, or their pharmaceutically acceptable salts as inhibitors of inducible NO-synthase.
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