发明名称 |
LIPOSOMAL FORMULATIONS AND RELATED METHODS |
摘要 |
Novel liposomes have relatively high membrane phase-transition temperatures, and little or no residual organic solvent. They can be advantageously dried before use to produce proliposomes. Upon reconstitution and filling with 5-FU or other drugs, the resulting liposomes can carry an unusually high level of active drug, and exhibit especially good storage characteristics. Preferred topical creams and other formulations include at least 20 wt% liposomes, and no more than 0.75 wt%, 0.5 wt%, or even 0.25 wt% 5-FU.
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申请公布号 |
WO03039512(A1) |
申请公布日期 |
2003.05.15 |
申请号 |
WO2002US19984 |
申请日期 |
2002.06.21 |
申请人 |
DE PAOLI, TOMAS;HAGER, ALFREDO ADOLFO;FISH, ROBERT |
发明人 |
DE PAOLI, TOMAS;HAGER, ALFREDO ADOLFO |
分类号 |
A61K9/127;A61K31/505;A61K31/661;A61K31/685;B01L3/00;(IPC1-7):A61K9/127;A61K9/00 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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