发明名称 Ependymal neural stem cells and method for their isolation
摘要 The invention relates to an ependymal neural CNS stem cell, which cell expresses the surface protein Notch 1 together with at least one surface protein chosen from the group of Notch 2, Notch 3, CAR (transmembrane protein binding adenovirus) and CFTR cystic fibrosis transmembrane conductance regulator), and which cell also comprises at least one cilium. The invention also relates to preparations, including pharmaceutical preparations, comprising ependymal neural CNS stem cells, in vitro and in vivo assays based thereon and various other uses of the novel ependymal cells according to the invention.
申请公布号 US2003092176(A1) 申请公布日期 2003.05.15
申请号 US20020183728 申请日期 2002.06.27
申请人 NEURONOVA AB 发明人 JANSON ANN MARIE;FRISEN JONAS;JOHANSSON CLAS;MOMMA STEFAN;CLARKE DIANA;ZHAO MING;LENDAHL URBAN;DELFANI KIOUMARS
分类号 A61K35/12;A61K35/30;A61L27/00;A61P1/16;A61P1/18;A61P9/00;A61P9/10;A61P13/12;A61P21/00;A61P21/04;A61P25/00;A61P25/16;A61P25/28;A61P27/02;A61P27/16;A61P43/00;C12N5/0797;(IPC1-7):C12N5/08 主分类号 A61K35/12
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