MEDICINAL PREPARATION FOR SLIGHTLY SOLUBLE MEDICAMENT

摘要

PROBLEM TO BE SOLVED: To provide a bead dosage form capable of preventing the reduction of a dissolution rate when a capsule medicinal preparation is formed by filling the capsule with the beads, and further to provide the capsule medicinal preparation. SOLUTION: The bead is obtained by forming a covering layer on the periphery of a pharmaceutically inert nucleus out of a slightly soluble medicine and a hydrophilic polymer, or further partially or wholly covering the outer periphery of the coated water-soluble high-molecular polymer layer with an inorganic material.