发明名称 |
COMPOSITIONS AND METHODS FOR WT1 SPECIFIC IMMUNOTHERAPY |
摘要 |
Compositions and methods for the therapy of malignant diseases, such as leukemia and cancer, are disclosed. The compositions comprise one or more of a WT1 polynucleotide, a WT1 polypeptide, an antigen-presenting cell presenting a WT1 polypeptide, an antibody that specifically binds to a WT1 polypeptide; o r a T cell that specifically reacts with a WT1 polypeptide. Such compositions may be used, for example, for the prevention and treatment of metastatic diseases.
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申请公布号 |
CA2465303(A1) |
申请公布日期 |
2003.05.08 |
申请号 |
CA20022465303 |
申请日期 |
2002.10.30 |
申请人 |
CORIXA CORPORATION |
发明人 |
MCNEILL, PATRICIA D.;GAIGER, ALEXANDER;CARTER, DARRICK;JAYA, NOMALIE |
分类号 |
C12N15/09;A61K35/76;A61K38/00;A61K39/00;A61K48/00;A61P35/00;A61P35/02;C07K14/47;C07K14/82;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/08;C12N5/10;(IPC1-7):C12N15/62;C12N15/12;A61K38/17;C07K14/705 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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