7118, A HUMAN ARGININE N-METHYLTRANSFERASE FAMILY MEMBER AND USES THEREFOR

摘要

The invention provides isolated nucleic acids molecules, designated 7118 nucleic acid molecules, which encode novel arginine N-methyltransferase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 7118 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 7118 gene has been introduced or disrupted. The invention still further provides isolated 7118 proteins, fusion proteins, antigenic peptides and anti-7118 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.