| 摘要 |
A nutritional intervention composition is provided for enhancing the efficacy of an orally administered lipase inhibitor comprising a protein component of at least a glycomacropeptide or caseinmacropeptide, at least one C12-18 fatty acid comprising at least oleic acid and a fiber preferably comprising both soluble and insoluble fibers. The composition is administered concurrently with the lipase inhibitor to negate the action of the latter in inhibiting the release of cholecystokinin (CCK) which, in turn, reduces the feeling of satiety and stimulates appetite. These effects are all countered by the subject compositions which stimulate release of CCK and increase the level of bile in the intestine. These effects achieved by the subject nutritional intervention compositions, while not directly increasing the effectiveness of the lipase inhibitor, nonetheless enhance its efficacy.
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