PHARMACEUTICAL COMPOSITION FOR USE FOR THE TREATMENT OF MALIGNANCIES COMPRISING IN COMBINATION A BISPHOSPHONATES, A COX-2 INHIBITOR AND A TAXOL
摘要
A pharmaceutical composition for treatment of malignancies, in particular a malignant disease which is associated with the development of bone metastases or excessive bone resorption, comprises in combination a bisphosphonates, COX−2 inhibitor and/or a taxol or derivative thereof for simultaneous, sequential or separate use. Also provided is a method of treating a patient suffering from a malignant disease comprising administering to the patient an effective amount of a bisphosphonates, an effective amount of a COX−2 inhibitor and/or and effective amount of a taxol or derivative thereof.
申请公布号
WO03035081(A1)
申请公布日期
2003.05.01
申请号
WO2002EP11696
申请日期
2002.10.18
申请人
NOVARTIS AG;NOVARTIS PHARMA GMBH;GREEN, JONATHAN;LIPTON, ALLAN;WITTERS, LOIS, MARY