| 摘要 |
Novel SPOIL polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length SPOIL proteins, the invention further provides isolated SPOIL fusion proteins, antigenic peptides and anti-SPOIL antibodies. The invention also provides SPOIL nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a SPOIL gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
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