HUMAN AND MAMMALIAN STEM CELL-DERIVED NEURONAL SURVIVAL POLYPEPTIDES

摘要

Human, rat and mouse stem cell derived neuronal survival polypeptides (SDNSF); a process for producing the same; cDNA encoding SDNSF; a vector comprising this cDNA; host cells transformed by the vector; an SDNSF antibody; medicinal compositions containing SDNSF or the antibody; a method of assaying SDNSF; a reagent for assaying SDNSF; and a screening method using SDNSF. The above polypeptides are effective in the survival of nerve cells and, therefore, efficacious in treating injury in the central nerve system by brain infarction, brain hemorrhage, spinal injury, etc.