发明名称 |
COMPOSITIONS AND METHODS FOR REVERSAL OF DRUG RESISTANCE |
摘要 |
The present invention relates to sigma-1 recptor ligands, to uses of sigma-1 receptor ligands in treating drug resistance, methods of using sigma-1 receptor ligans in regulating P-glycoprotein expression, methods of screening for compositions (e.g., agonists) that activate the sigma-1 receptor, regulate P-glycoprotein expression and/or have tolerance reducing activity. |
申请公布号 |
WO03032926(A2) |
申请公布日期 |
2003.04.24 |
申请号 |
WO2002US33551 |
申请日期 |
2002.10.21 |
申请人 |
MEMORIAL SLOAN-KETTERING CANCER CENTER;PASTERNAK, GAVRIL, W.;NEILAN, CLAIRE |
发明人 |
PASTERNAK, GAVRIL, W.;NEILAN, CLAIRE |
分类号 |
A61K31/00;A61K31/136;A61K31/337;A61K31/40;A61K31/439;A61K31/475;A61K31/522;A61K31/537;A61K31/5375;A61K31/55;A61K31/704;A61K38/04;A61K45/06 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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