发明名称 |
FAT-BINDING POLYMERS COMBINED WITH LIPASE INHIBITORS FOR THE TREATMENT OF OBESITY |
摘要 |
<p>The present invention relates to a method for treating obesity, a method for reducing the absorption of dietary fat, and a method for treating hypertriglyceridemia in a patient and to particular polymers for use in the methods or in a manufacture of a medicament. The methods comprise the step of orally administering to a mammal, such as a human, a therapeutically effective amount of one or more fat-binding polymers. The administration of the fat-binding polymer of the invention facilitates the removal of fat from the body prior to digestion, with minimal side effects and low toxicity. In a preferred embodiment, the one or more fat-binding polymers are administered in combination with one or more lipase inhibitors, for example, lipstatin and tetrahydrolipstatin.</p> |
申请公布号 |
EP1043981(B1) |
申请公布日期 |
2003.04.16 |
申请号 |
EP19990900369 |
申请日期 |
1999.01.04 |
申请人 |
GELTEX PHARMACEUTICALS, INC. |
发明人 |
MANDEVILLE, W., HARRY, III.;WHITESIDES, GEORGE, M.;HOLMES-FARLEY, STEPHEN, RANDALL |
分类号 |
A61K31/74;A61K31/205;A61K31/765;A61K31/78;A61K31/785;A61P3/04;(IPC1-7):A61K38/46;A61K45/06 |
主分类号 |
A61K31/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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