PEPTIDOGLYCAN RECOGNITION PROTEIN ENCODING NUCLEIC ACIDS AND METHODS OF USE THEREOF

摘要

Novel human PGRP genes and their encoded proteins are provided herein. The peptidoglycan recognition proteins encoded by the disclosed nucleic acid sequences play a pivotal role in the innate immune response. PGRP genes and their encoded proteins provide valuable therapeutic targets for the design of agents which modulate the immune response to bacterial infection.