发明名称 N-HETEROCYCLYL HYDRAZIDES AS NEUROTROPHIC AGENTS
摘要 This invention relates to a series of N-heterocyclyl hydrazides of Formula I , and pharmaceutically compositions containing them. The compounds of the invention have neurotrophic activity and are useful in the treatment and prevention of neuronal disorders such as Parkinson's disease,Alzheimer's disease, stroke, multiple sclerosis, amyotrophic lateral sclerosis diabetic neuropathy and Bell's palsy.
申请公布号 CA2462419(A1) 申请公布日期 2003.04.10
申请号 CA20022462419 申请日期 2002.10.04
申请人 ORTHO-MCNEIL PHARMACEUTICAL, INC. 发明人 MACIELAG, MARK;LANTER, JAMES C.;SUI, ZHIHUA
分类号 A61K31/38;A61K31/415;A61K31/4155;A61K31/435;A61K31/437;A61K31/44;A61K31/4427;A61K31/4439;A61K31/4545;A61K31/47;A61K31/4709;A61P3/10;A61P9/00;A61P21/00;A61P25/00;A61P25/02;A61P25/16;A61P25/28;A61P43/00;C07B61/00;C07D401/12;C07D403/12;C07D409/14;C07D471/04;(IPC1-7):C07D401/12;C07D205/00;C07D207/00;C07D211/00;C07D213/00;C07D215/00;C07D221/00;C07D231/00;C07D333/00 主分类号 A61K31/38
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