Method and system for measuring T-wave alternans by alignment of alternating median beats to a cubic spline

摘要

An electrocardiogram processing technique for measuring T-wave alternans by which the alternating electrocardiogram signals are aligned to a target cubic spline. The target cubic spline is calculated on base of three isoelectric points namely a point before the P-wave, a point before the QRS-complex and a point after the T-wave. The aligned signals may then be further analyzed for variations such as T-wave alternans which are only present in alternating beats and which have diagnostic significance.