发明名称 |
ENHANCED REPLICATION OF HCV RNA |
摘要 |
This invention provides methods for generating cells that stably replicate sub-genomic virus replicons. This invention also provides methods of generating cells that have disabled PKR activity and that stably replicate HCV subgenomic replicons. The invention also provides methods of using the cells of the invention to screen for compounds that modulate viral RNA replication, including HCV RNA replication. |
申请公布号 |
WO0212477(A3) |
申请公布日期 |
2003.04.10 |
申请号 |
WO2001US24276 |
申请日期 |
2001.08.03 |
申请人 |
CHIRON CORPORATION;LU, HUI-HUA;SELBY, MARK |
发明人 |
LU, HUI-HUA;SELBY, MARK |
分类号 |
C12N5/08;C12N7/00;C12N9/12;C12N15/69;C12N15/86 |
主分类号 |
C12N5/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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