PROBE COMPOSITIONS FOR CHROMOSOME IDENTIFICATION AND METHODS

摘要

Direct label probe compositions which stain DNA of a preselected single chromosome or region of a chromosome of a multi-chromosomal genome are provided that comprise mixed DNA segments which are covalently bound to fluorophore groups through linking groups. The mixed DNA segments are derived from the DNA present in the preselected chromosome or chromo- some region. These probe compositions can be used concurrently or sequential ly with other probe compositions.