发明名称 NOUVEAUX OLIGOMERES D'UREES, LEUR PROCEDE DE PREPARATION ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT
摘要 The invention relates to the use of compounds having general formula X-(A)n-Y, wherein: n varies between 6 and 20; X denotes a hydrogen atom, an RaCO, RaOCO, RaNHCO or RaSO2 group, Ra being an alkyl, alkenyl, alkynyl, aryl, aralkyl, heteroaryl group, said groups being substituted or not, on condition that X is different from H when n is equal to 6; A denotes either a group having formula (I) or (II), wherein R<i> is a hydrogen atom, an amino acid side chain, an alkyl, alkenyl, alkynyl, aryl, aralkyl or heteroaryl group, said groups being substituted or not, i being an integer of between 1 and n; Y is an NRbRc, Rb and Rc group having the same meaning as given earlier for Ra. Said compounds are used for the preparation of medicaments that are intended to treat bacterial, fungal or cytotoxic diseases and, in particular, fungal infections, such as aspergillosis and candidiasis, and resistant bacterial infections.
申请公布号 FR2830252(A1) 申请公布日期 2003.04.04
申请号 FR20010012659 申请日期 2001.10.02
申请人 CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 发明人 GUICHARD GILLES FRANCOIS ROGER;BRIAND JEAN PAUL;SEMETEY VINCENT;NEUBERG PATRICK
分类号 C07D311/90;A61K31/17;A61K31/352;A61P31/00;A61P31/04;A61P31/10;A61P35/00;C07C275/24;C07C279/12;C07C323/60;C07D311/82;(IPC1-7):C07C275/24 主分类号 C07D311/90
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