发明名称 BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC ANDDERIVATIVES THEREOF
摘要 Oxazolidinones having a bicyclic[3.1.0]hexane containing moiety, which are effective against aerobic and anerobic pathogens such as multi-resistant staphylococci, Streptococci and enterococci, Bacteroides spp., Clostridia spp.species, as well as acid-fast organisms such as MYCOBACTERIUM TUBERCULOSISand other mycobacterial species. The compounds are represented b y structural formula I: its enantiomer, diastereomer, or pharmaceutically acceptable salt or ester thereof, and wherein the variables R1, R2, R3, R4a, A, Ar, HAr, n, r, and s are as defined herein.
申请公布号 CA2443410(A1) 申请公布日期 2003.04.03
申请号 CA20022443410 申请日期 2002.04.17
申请人 KYORIN PHARMACEUTICAL CO., LTD.;MERCK & CO., INC. 发明人 HAMMOND, MILTON L.;FUKUDA, YASUMICHI
分类号 C07D263/20;A61K31/421;A61K31/422;A61P31/04;C07D263/10;C07D263/24;C07D405/10;C07D413/10;C07D413/14;(IPC1-7):C07D263/24 主分类号 C07D263/20
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